A nurse provides teaching to a patient who will begin taking oral cyclophosphamide to treat non-Hodgkin's lymphoma. Which statement by the patient indicates an understanding about how to minimize side effects while taking this drug?
a. "I don't need to worry about bone marrow suppression with this drug."
b. "I should drink plenty of fluids while taking this drug."
c. "I should take this drug on an empty stomach."
d. "If I shampoo less often, I can prevent hair loss."
ANS: B
Acute hemorrhagic cystitis can occur; this can be minimized by maintaining adequate hydration and taking mesna (Mesnex), a protective agent. Bone marrow suppression is a dose-limiting side effect. This drug should be taken with food. Hair loss cannot be prevented by shampooing less often.
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