A woman at 26 weeks of gestation is being assessed to determine if she is experiencing preterm labor. Which of the following findings indicates that preterm labor is occurring?

Question

1. Estriol is not found in maternal saliva.
2. Irregular mild uterine contractions are occurring every 12 to 15 minutes.
3. Fetal fibronectin is present in vaginal secretions.
4. The cervix is effacing and dilated to 2 cm.

Answer 1

4
1. Incorrect. Estriol is a form of estrogen produced by the fetus that is present in plasma at 9 weeks of gestation. Levels of salivary estriol have been shown to increase before preterm birth.
2. Incorrect. Irregular mild contractions that do not cause cervical change are not considered a threat.
3. Incorrect. The presence of fetal fibronectin in vaginal secretions between 24 and 36 weeks of gestation could predict preterm labor but has only a 20% to 40% positive predictive value. Of more importance are other physiologic clues of preterm labor, such as cervical changes.
4. Correct. Cervical changes such as shortened endocervical length, effacement, and dila-tion are predictors of imminent preterm labor. Changes in the cervix accompanied by regular contractions indicate labor at any gestation.