Patients who have a deficiency of protein C or protein S have which type of disorder?
a. Bleeding disorder
b. Thrombotic disorder
c. Bruising disorder
d. Hypercalcemia
ANS: B
Patients with a deficiency of either protein C or protein S have a thrombotic disorder. These two proteins are important in regulating, by downgrading, thrombin generation and thus clotting. Activated protein C binds free protein S to form a complex that inactivates factors Va and VIIIa.
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