Explain how the loss of heterozygosity (LOH) leads a cell to become cancerous
What will be an ideal response?
An individual in a heterozygous condition with a predisposition to cancer, may have a mutant allele present in the germ cells and all the somatic cells. A mutation in the other, normal allele of the gene might occur, causing the cell to become cancerous. This mutational event is known as loss of heterozygosity.
You might also like to view...
The cross section in the accompanying figure is representative of the internal structures found in:
a. phoronids. b. nemerteans. c. gastropods. d. flatworms. e. oligochaetes
Mollusks and arthropods have closed circulatory systems.
Answer the following statement true (T) or false (F)
A zygosporangium is produced by
A) the union of two haploid hyphae. B) meiosis of megaspores. C) mitosis of hyphae. D) the union of egg and sperm. E) meiosis of hyphae.
What percentage of the water that enters a nephron is reabsorbed into the blood in the absence of ADH?
A) 50% B) 25% C) 99% D) 80%