What is the most common pulmonary function abnormality found in patients with idiopathic pulmonary artery hypertension (IPAH)?

a. Reduced diffusing capacity of the lungs (DLCO)
b. Reduced forced vital capacity (FVC)
c. Reduced forced expiratory flow (FEF25% to 75%)
d. Reduced lung compliance (CL)


ANS: A
Pulmonary function tests are useful to rule out the presence of significant restrictive or obstruc-tive airway disease. The most common abnormality at pulmonary function testing of patients with IPAH is a low carbon monoxide diffusing capacity (DLCO).

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