Match the description in questions 1-5 with the lettered item (A-I) related to antigen-presentation pathways

A. T cell receptor on CD4+ T cells
B. Endosomes
C. Endoplasmic reticulum
D. MHC class II compartment/class II vesicle (MIIC/CIIV)
E. Class II-associated invariant chain peptide (CLIP)
F. LMP-2 and LMP-7
G. Acidic proteases
H. T cell receptor on CD8+ T cells
I. HLA-DM

Site of proteolysis of antigens in the class II MHC pathway


ANS: B. Endosomes are membrane-bound acidic vesicles in which internalized proteins are proteolytically degraded in the class II MHC pathway.

Health & Biomechanics

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