A nurse is providing education to a group of new mothers regarding medications for their children. The nurse is correct to tell the mothers that in terms of medication absorption
a. gastric acidity does not reach adult levels until around 2 years of age.
b. an intramuscular injection is quickly absorbed in the neonate.
c. drug absorption through the skin is lower than in adults and older children.
d. renal drug excretion is increased at birth.
A
Gastric acidity does not reach adult levels until 2 years of age and therefore is less likely to break down medications in children younger than 2 years. Dosing is critical, because a child younger than 2 years has greater absorption and therefore needs lower dosing of medications.
Intramuscular injections are generally contraindicated in neonates because of their minimal mus-cle development. The exception is the administration of Aquamephyton (vitamin K), which is administered in the largest muscle, the vastus lateralis, to enhance absorption.
Drug absorption through the skin is higher in younger children than in adults and older children because of their thin skin.
Renal drug excretion is decreased at birth because of the immaturity of the organs.
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