Leukemias are classified according to the predominant cell type. The myelogenous cell type of leukemia can:
A) Interfere with thrombocyte cell maturation
B) Originate in marrow and infiltrate nodes
C) Affect B and T stem cells in bone marrow
D) Transform mature cells into immature ones
Ans: A
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Myelogenous leukemia interferes with maturation of all blood cells, including granulocytes, erythrocytes, and thrombocytes, in the bone marrow. Lymphocytic leukemia originates in the marrow and infiltrates the spleen, lymph nodes, and tissues. Lymphocytic leukemia has immature precursor B and T cells in the marrow. Chronic lymphocytic leukemia results from the malignant transformation of relatively mature B lymphocytes into immature ones.
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