Somatic mutations are initiated in V gene segments by the creation of abasic sites. Why does the repair of these introduce more mutations than similar repairs at other sites?

What will be an ideal response?


Ans: The repair, which may take place by several mechanisms, involves an error-prone DNA polymerase that introduces more mutations, perhaps by randomly inserting bases.

Biology & Microbiology

You might also like to view...

Answer the following statements true (T) or false (F)

1. Friedrich Wöhler refuted the scientific concept of vitalism during the early 1800s by proving that organic molecules could be synthesized outside a living organism. 2. Since carbon and hydrogen share similar electronegativities they will form nonpolar molecules when combined. 3. Macromolecules such as lipids and carbohydrates are produced from simple subunits through condensation reactions. 4. The sole function of carbohydrates is to serve as energy stores.

Biology & Microbiology

Salmon fisheries are located in the coastal waters of:

a. Alaska. b. New England. c. the Pacific Northwest. d. China. e. both a and c

Biology & Microbiology

What fleshy projection is an adaptation some fish have to lure prey in?

a. Barbel b. Antennae c. Photophore d. Appendage

Biology & Microbiology

The enzyme ____________________ converts prothrombin to thrombin. Fill in the blank(s) with the appropriate word(s)

Biology & Microbiology