Tumor-induced angiogenesis is promoted by
A. vascular endothelial growth factor (VEGF)
B. thrombospondin
C. endostatin
D. vasostatin
E. angiostatin
A
VEGF, a secretory product of many cells, promotes angiogenesis by binding to receptors on endothelial cells. VEGF promotes endothelial cell growth, migration, and vessel formation. Thrombospondin (platelet factor 4), angiostatin (cleavage product of plasminogen), endostatin (cleavage product of collagen type XVIII), and vasostatin (cleavage product of calretinin) prevent angiogenesis.
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The plural of breath is ________.
Fill in the blank(s) with the appropriate word(s).
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Indicate whether the statement is true or false