The patient is receiving cholestryamine (Questran), and complains of constipation. The physician orders bisacodyl (Ducolax) tablets. When is the best time for the nurse to administer the bisacodyl (Ducolax) tablets?
1. The drugs can be administered together.
2. Four hours after administration of cholestryamine (Questran)
3. Bisacodyl (Ducolax) can be given any time, but must be taken with food.
4. One hour after administration of cholestryamine (Questran)
Correct Answer: 2
Rationale: Other drugs must be administered more than 2 hours before, or 4 hours after, the patient takes cholestryamine (Questran) because it can bind to other drugs and interfere with their absorption. These drugs cannot be administered together because cholestryamine (Questran) can bind to other drugs and interfere with their absorption. A minimum of 4 hours administration time between drugs is needed to be sure cholestryamine (Questran) does not interfere with absorption of other drugs. Bisacodyl (Ducolax) cannot be administered with cholestryamine (Questran) as it will not be absorbed; Bisacodyl (Ducolax) does not need to be given with food.
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