A nurse is teaching a group of nursing students about neurotransmitters. Which statement by a student about acetylcholine indicates a need for further teaching?
a. "It activates three cholinergic receptor subtypes."
b. "It has effects in the parasympathetic, sympathetic, and somatic nervous sys-tems."
c. "It is used at most junctions of the peri-pheral nervous system."
d. "Its transmission is terminated by reuptake into the cholinergic nerve terminal."
D
Acetylcholine (ACh) is destroyed by acetylcholinesterase, an enzyme that degrades ACh into two inactive products: acetate and choline. Choline is taken up into the nerve terminal. ACh ac-tivates three receptor sites: nicotinicN, nicotinicM, and muscarinic. ACh has effects throughout the peripheral nervous system (PNS) and is used at most junctions in the PNS.
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