What type of insulin is administered at bedtime, either with or without another type of insulin?

Question

1. Insulin glargine (Lantus)
2. Insulin isophane (Humulin N)
3. Insulinglulisine (Apidra)
4. NPH 70/30 (Humulin 70/30)

Answer 1

1

Rationale 1:Insulin glargine (Lantus) is an insulin analog, given at bedtime.
Rationale 2:Insulin isophane (Humulin N)is usually given in the mornings and before the evening meal.
Rationale 3:Insulin glulisine (Apidra) is administered before a meal or within 20 minutes of starting a meal.
Rationale 4:NPH 70/30 (Humulin 70/30) is incorrect because NPH 70/30 is a mixed preparation, with onset, peak, and duration similar to insulin isophane (Humulin N).

Global Rationale: Insulin glargine (Lantus) is an insulin analog, given at bedtime. Insulin detemir (Levemir) is a long-acting insulin given with the evening meal or at bedtime.