To prevent Rh isoimmunization, RhIG (RhoGAM) is administered to all:

a. Rh-negative women who deliver an Rh-positive newborn.
b. Rh-positive women who deliver an Rh-negative newborn.
c. Rh-negative newborns whose mothers are Rh positive.
d. Rh-positive fathers before conception of second newborn when first newborn was Rh positive.


ANS: A
Rh IG human gamma globulin concentrate of anti-D is administered to all unsensitized Rh-negative women after delivery or abortion of an Rh-positive newborn or fetus. Administering RhIG to an individual who is Rh positive will result in agglutination of red cells and hemolysis. It will not alter the person's genetic makeup. The anti-D antibody contained in RhIG will have no effect on Rh-negative newborns because the D antibody is not present.

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