Which drug(s) interact(s) with SSRI agents? (Select all that apply.)

a. Tranylcypromine (Parnate)
b. Lithium (Eskalith)
c. Warfarin (Coumadin)
d. Furosemide (Lasix)
e. Propranolol (Inderal)


ANS: A, B, C, E
A 14-day lapse is recommended between MAOIs, such as Parnate, and SSRI agents.
The incidence of lithium toxicity is increased with SSRI agents. The anticoagulant effects of warfarin may be enhanced with SSRIs. The SSRIs fluvoxamine and citalopram inhibit the metabolism of beta-adrenergic blocking agents such as propranolol. Lasix does not interact with SSRI agents.

Nursing

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