The first signal during helper T-lymphocyte activation involves
A. BCR of the helper T-cell binding with free antigen and engulfing it.
B. CD8 of the helper T-cell binding with MHC class III of the antigen-presenting cell.
C. CD4 of the helper T-cell binding with MHC class I part of the antigen fragment.
D. CD4 of the helper T-cell binding with MHC class II of the antigen-presenting cell.
D
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