What was the first major disease to be prevented by inoculation?
1. Polio
2. Anthrax
3. Smallpox
4. Measles
Correct Answer: 3
Rationale 1: Polio was not the first disease to be prevented by inoculation.
Rationale 2: Anthrax was not the first disease to be prevented by inoculation.
Rationale 3: The first major disease to be prevented by inoculation was smallpox.
Rationale 4: Measles was not the first disease to be prevented by inoculation.
Global Rationale: In the 1790s, Dr. Edward Jenner was experimenting with the use of inoculation, the placement of a foreign substance on or in an individual for the purpose of disease prevention. Inoculation uses live virus particles obtained from an infected patient. Jenner used the cowpox virus, a benign pathogen in humans, because he predicted that exposure to that virus would provide immunity to smallpox, which was one of the most dreaded human diseases of that era. Jenner's inoculation of a single 8-year-old boy ultimately led to one of the greatest triumphs in disease prevention. Vaccines for polio, anthrax, and measles were developed later.
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