Baby frog #1 is homozygous for a mutant allele of gene B (allele b1). Compare the DNA sequence from baby frog #1 with the wild-type sequence to determine how allele b1 is different from the wild-type. What effect does the mutation in allele b1 have on the protein?







A) Allele b1 has a frameshift mutation—a deletion of one nucleotide resulting in a frameshift that changes all amino acids from that point on.

B) Allele b1 has a deletion of one nucleotide outside of the coding region and there is not effect on the protein.

C) Allele b1 has a missense mutation—a nucleotide substitution that changes one amino acid to another.

D) Allele b1 has a nonsense mutation—a nucleotide substitution that forms a stop codon.

E) Allele b1 has a nucleotide substitution that does not change the protein.


A) Allele b1 has a frameshift mutation—a deletion of one nucleotide resulting in a frameshift that changes all amino acids from that point on.

Biology & Microbiology

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