What important point(s) of patient education should be included about disulfiram (Antabuse) therapy? (Select all that apply.)
a. The patient should return for liver function tests in 10 to 14 days following initiation of therapy.
b. Headache, fatigue, and a metallic taste are common adverse effects that usually resolve.
c. Avoid alcohol ingestion to prevent a reaction.
d. Carefully read all labels for possible alcohol content, including perfumes and over-the-counter (OTC) medications such as cough syrups.
e. Report to the health care provider any allergic symptoms, such as hives or pruritus.
ANS: A, B, C, D
Baseline laboratory data include liver function tests and alcohol screening. Headache, fatigue, and a metallic taste are common adverse effects of disulfiram. Disulfiram is a drug used to treat chronic alcoholism that produces a very unpleasant reaction to alcohol. Patients should be instructed to read all labels of topical substances and OTC drugs for alcohol content, as well as avoiding any foods that may be prepared with alcohol. Disulfiram is unlikely to cause allergic reactions.
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