An acute leukemia patient presents with blast morphology that is of neutrophil lineage with Auer rods and pseudo-Pelger-Huà«t nuclei, myeloperoxidase, and Sudan Black B

Cytogenetic analysis reveals a t(8;21)(q22;q22) translocation in the majority of the blasts.
Which classification of AML best fits this morphology, immunophenotyping, and cytochemistry? Which classification of AML best fits this morphology, immunophenotyping, and cytochemistry?

a. AML not otherwise categorized
b. AML with multilineage dysplasia
c. AML with recurrent genetic abnormalities
d. AML, therapy-related


Correct Answer: C

Health Professions

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