Treatment with an antipsychotic medication is being considered for an older adult client with dementia-related psychosis. Which medication would not be appropriate for this client?
1. Olanzapine (Zyprexa)
2. Clozapine (Clozaril)
3. Loxapine (Loxitane)
4. Aripiprazole (Abilify)
Correct Answer: 4
Rationale 1: Zyprexa is used to treat behavioral symptoms associated with dementia of Alzheimer disease.
Rationale 2: Clozapine is approved for dementia-related behavioral disorder.
Rationale 3: Loxapine is used off-label to treat severe behavioral disturbances associated with Alzheimer disease.
Rationale 4: Older adult clients with dementia-related psychosis have an increased risk of death due to stroke and other cardiovascular disorders when taking Abilify.
Global Rationale: Older adult clients with dementia-related psychosis have an increased risk of death due to stroke and other cardiovascular disorders when taking Abilify. Zyprexa is used to treat behavioral symptoms associated with dementia of Alzheimer disease. Clozapine is approved for dementia-related behavioral disorder. Loxapine is used off-label to treat severe behavioral disturbances associated with Alzheimer disease.
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