The physician has opted to treat a patient with a complete spinal cord injury with glucocorticoids. The physician orders 30 mg/kg over 15 minutes followed in 45 minutes with an infusion of 5.4 mg/kg/min for 23 hours
What is the total 24-hour dose for the 70-kg patient? a. 2478 mg
b. 5000 mg
c. 10,794 mg
d. 12,750 mg
C
The dosing regimen is initiated with a bolus of 30 mg/kg over 15 minutes, followed in 45 minutes by a continuous intravenous infusion of 5.4 mg/kg/hr for 23 hours. (30 mg ? 70 kg) + (5.4 mg ? 70 kg) ? 23 hours = 10,794 mg.
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