The client with breast cancer has been given a prescription for cyclophosphamide (Cytoxan). The nurse determines that the client understands the proper use of the medication if the client states that he or she will:
1. Increase dietary intake of potassium.
2. Take the medication with large meals.
3. Decrease dietary intake of magnesium.
4. Increase fluid intake to 2 to 3 L/day.
4
Rationale: A toxic effect of cyclophosphamide (Cytoxan) is hemorrhagic cystitis. The client should drink large amounts of fluid during the administration of this medication. Clients also should observe for hematuria. The medication should be taken on an empty stomach, unless gastrointestinal upset occurs. Hyperkalemia can result from the use of the medication; therefore, the client would not be encouraged to increase potassium intake. The client would not be instructed to alter magnesium intake.
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