A sputum culture has been collected and sent for culture and sensitivity. The physician orders a broad-spectrum antibiotic. What is the reason this medication is being ordered?
1. The culture and sensitivity will take 2 weeks for the results to be available.
2. Treatment for severe infections is started on broad-spectrum antibiotics while the culture is pending and then changed to a narrow-spectrum antibiotic.
3. Most people are allergic to narrow-spectrum antibiotics.
4. The broad-spectrum antibiotic will cure the infection before the culture results are ready.
Correct Answer: 2
Rationale 1: The culture and sensitivity will take 2 weeks for the results to be available is incorrect. This only takes a few days.
Rationale 2: Ideally, the pathogen should be identified before anti-infective therapy is begun. However, laboratory testing and identification may take several days or, in the case of viruses, several weeks. If the infection is severe, therapy is often begun with a broad-spectrum antibiotic, one that is effective against a wide variety of different microbial species. After laboratory testing is completed, the drug may be changed to a narrow-spectrum antibiotic, one that is effective against a smaller group of microbes or only the isolated species. In general, narrow-spectrum antibiotics have less effect on normal host flora, causing fewer adverse effects.
Rationale 3: Most people are allergic to narrow-spectrum antibiotics is incorrect. The broad-spectrum antibiotic is started while the culture is pending, and then the most effective antibiotic is used.
Rationale 4: The broad-spectrum antibiotic will cure the infection before the culture results are ready is incorrect. The broad-spectrum antibiotic is started while the culture is pending, and then the most effective antibiotic is used.
Global Rationale: Ideally, the pathogen should be identified before anti-infective therapy is begun. However, laboratory testing and identification may can several days or, in the case of viruses, several weeks. If the infection is severe, therapy is often begun with a broad-spectrum antibiotic, one that is effective against a wide variety of different microbial species. After laboratory testing is completed, the drug may be changed to a narrow-spectrum antibiotic, one that is effective against a smaller group of microbes or only the isolated species. In general, narrow-spectrum antibiotics have less effect on normal host flora, causing fewer adverse effects. The culture and sensitivity will take 2 weeks for the results to be available is incorrect. This only takes a few days. Most people are allergic to narrow-spectrum antibiotics is incorrect. The broad-spectrum antibiotic is started while the culture is pending, and then the most effective antibiotic is used. The broad-spectrum antibiotic will cure the infection before the culture results are ready is incorrect. The broad-spectrum antibiotic is started while the culture is pending, and then the most effective antibiotic is used.
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