A male client who is prescribed Sildenafil (Viagra) asks the nurse how the medication works. What is the nurse's best response?
1. "It causes an erection to occur."
2. "It restricts blood flow to the penis."
3. "It stimulates the release of phosphodiesterase-5, an enzyme that causes an erection."
4. "It inhibits the release of an enzyme that relaxes smooth muscle in the penis to allow blood flow leading to an erection."
Correct Answer: 4
Rationale 1: Sildenafil (Viagra) does not cause an erection.
Rationale 2: Sildenafil (Viagra) does not restrict blood flow to the penis.
Rationale 3: Sildenafil (Viagra) does not stimulate the release of phosphodiesterase-5.
Rationale 4: Sildenafil (Viagra) inhibits the release of phosphodiesterase-5, which relaxes smooth muscle in the corpus cavernosa and allows an increase of blood flow to the penis, causing an erection.
Global Rationale: Sildenafil (Viagra) inhibits the release of phosphodiesterase-5, which relaxes smooth muscle in the corpus cavernosa and allows an increase of blood flow to the penis, causing an erection. The medication itself does not cause an erection. It does not restrict blood flow to the penis and does not stimulate release of phosphodiesterase-5.
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