A patient is being treated with dapsone, an antibiotic, for P. carinii infection. Which of the fol-lowing ways of measuring oxygen saturation would be most appropriate?
a. In vivo blood gas monitoring c. Pulse oximetry
b. In vitro blood gas monitoring d. CO-oximetry
ANS: D
The use of dapsone causes an increase in metHb, which will interfere with the accuracy of a pulse oximeter. The presence of metHb will decrease the actual saturation of Hb. Therefore, direct measurement of O2Hb is most appropriate in this case. A CO-oximeter will not only measure the O2Hb, but it will also measure the metHb level.
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