A 71-year-old male patient with a history of myocardial infarction (MI) and peripheral vascular disease (PVD) has been advised by his family physician to begin taking 81 mg aspirin once daily
Which of the following statements best captures an aspect of the underlying rationale for the physician's suggestion?
A)
Platelet aggregation can be precluded through inhibition of prostaglandin production by aspirin.
B)
Aspirin helps to inhibit ADP action and minimizes platelet plug formation.
C)
Aspirin can reduce unwanted platelet adhesion by inhibiting TXA2 synthesis.
D)
Aspirin inhibits the conversion of fibrinogen into fibrin and consequent platelet plug formation.
Ans:
A
Feedback:
Aspirin prevents platelet plug formation by inhibiting synthesis of prostaglandins that mediate clot formation. Aspirin does not influence ADP, TXA2 synthesis, or fibrinogen conversion.
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