A cell with nuclear lamins that cannot be phosphorylated in M phase will be unable to ________________

(a) reassemble its nuclear envelope at telophase.
(b) disassemble its nuclear lamina at prometaphase.
(c) begin to assemble a mitotic spindle.
(d) condense its chromosomes at prophase.


(b) If the lamins cannot be phosphorylated during mitosis, the cells will be unable to disassemble their nuclear lamina, preventing the breakdown of the nuclear envelope at prometaphase. The mitotic spindle begins to form before the nuclear envelope breaks down, forming a sort of cage around the nucleus [choice (c)]. Lamins are not involved in chromosome condensation [choice (d)].

Biology & Microbiology

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