All members of the steroid hormone receptor family __________________

(a) are cell-surface receptors.
(b) do not undergo conformational changes.
(c) are found only in the cytoplasm.
(d) interact with signal molecules that diffuse through the plasma membrane.


Choice (d) is correct. All members of the steroid hormone receptor family are intracellular proteins [thus choice (a) is not correct] that interact with signal molecules that can diffuse through the plasma membrane. Once activated, steroid hormone receptors regulate gene transcription in the nucleus [choice (c)]. The binding of the signal molecule induces a large conformational change in the receptor protein [choice (b)]. This conformational change activates the steroid hormone receptors, allowing them to promote or inhibit the transcription of the appropriate genes.

Biology & Microbiology

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What will be an ideal response?

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