Each of the following statements regarding B lymphocytes is TRUE except
A) B cells mature in the bone marrow and then leave to populate germinal centers in the
secondary lymphoid tissue (spleen, lymph nodes, etc.).
B) Rearrangements of VDJ heavy chain genes and VJ light chain genes appear to be
completely random.
C) When B cells encounter their corresponding antigen, they undergo rapid proliferation and
conversion to plasma cells.
D) A B cell is considered to be fully matured when it is secreting antibody.
D
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