A patient with a diagnosis of active TB has begun second-line therapy that includes the use of pyrazinamide

When monitoring this patient, the nurse should suspect that adverse effects of this drug may account for which of the following laboratory values? A) Low hematocrit and mean corpuscular volume (MCV)
B) Increased INR and aPTT
C) Increased blood urea nitrogen and creatinine
D) Increased AST, ALT, and GGT


D
Feedback:
The most severe adverse effect of pyrazinamide is hepatotoxicity. Consequently, liver enzymes such as GGT, ALT, and AST should be monitored. Changes in erythrocytes, coagulation, and renal function are less likely to result from pyrazinamide therapy.

Nursing

You might also like to view...

An 80-year-old patient has been prescribed an anticholinergic agent for treatment of Parkinson-related symptoms. What patient education should be provided?

A) "Avoid high environmental temperatures." B) "Anticholinergics increase mental alertness." C) "It is safe to take Sudafed for a cold." D) "You may experience urinary incontinence."

Nursing

Following a thyroidectomy, a patient complains of "a tingling feeling around my mouth." Which assessment should the nurse complete immediately?

a. Presence of the Chvostek's sign b. Abnormal serum potassium level c. Decreased thyroid hormone level d. Bleeding on the patient's dressing

Nursing

Identify the family type that has a father, daughter, and stepmother:

1. Blended. 2. Nuclear. 3. Traditional Nuclear family. 4. Bi-nuclear family.

Nursing

Two hours after taking a dose of penicillin, a patient arrives in the emergency department complaining of tightness in the throat, pruritus, and red wheals

During the physical assessment, the patient develops difficulty breathing, respirations 36/min, blood pressure 90/42, pulse rate of 120/min. The priority nursing action would be to a. administer diphenhydramine (Benadryl), because the patient is experiencing a moderate allergic reaction that should improve shortly. b. sit the patient up in bed, administer oxygen until the symptoms subside, and notify the prescriber. c. question the patient about any previous allergy to penicillin and report the symptoms to the prescriber. d. call for assistance, apply oxygen, administer epinephrine as ordered, and notify the prescriber.

Nursing