In cells with a normally functioning CFTR molecule, this molecule moves chloride ions (with

a negative charge) out of the cell to the covering mucus on the outside. Positively charged
sodium ions then follow these chloride ions out of the cell to maintain electrical balance. This
increases the total electrolyte concentration in the mucus, resulting in the movement of water
out of the cell, and this water helps provide a fluid environment. People that have a defective
gene (and thus a nonfunctioning CFTR molecule) produce abnormally thick and sticky mucus
that builds up in the ducts and passageways. The buildup of this sticky mucus results in lifethreatening
lung infections and serious digestive problems.
Many charged particles such as ions cannot pass directly across the plasma membrane.
Thus, passive transport of the chloride and sodium ions occurs via what process?



a. facilitated diffusion
b. active transport
c. bulk transport
d. osmosis


A

Biology & Microbiology

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