Which is a serious adverse effect of decongestants?
a. Hypotension
b. Hypertension
c. Orbital edema
d. Facial flushing
ANS: B
Sympathomimetic decongestants cause stimulation of the alpha-adrenergic receptors that can increase blood pressure. Excessive use of decongestants when taking a beta-adrenergic blocking agent or monoamine oxidase inhibitor can cause significant hypertension. Alpha receptor stimulation does not cause hypotension, orbital edema, or facial flushing.
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