A patient diagnosed with bipolar disorder asks the nurse, "Why can't I take my lithium just once a day at bedtime? It's hard to remember to take it three times." The nurse's reply should be based on what information?

a. The half-life of lithium is short.
b. Renal excretion is greater at night.
c. GI absorption is diminished at night.
d. The toxicity potential increases with once-a-day dosing.


A
Lithium has a short half-life, high toxicity, and rapid renal excretion, so multiple daily doses are required. The other statements are incorrect or are not factors considered in dosing.

Nursing

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