Which of the following processes is a component of the pathogenesis of proliferative breast lesions without atypia?
A) Growth of ductile or lobular epithelial cells
B) Cystic dilation of terminal ducts
C) Increase in fibrous breast tissue
D) Fat necrosis leading to lesion formation
Ans: A
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Proliferative lesions without atypia are characterized by proliferation of ductile or lobular epithelial cells. Dilation of the terminal milk ducts and a general increase in fibrous breast tissue are associated with fibrocystic breast changes. Fat necrosis is not implicated in the development of proliferative breast lesions without atypia.
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