A patient who requires repeated dosing with strong analgesics over a period of more than a few days might be prescribed which of the following secondary plant metabolites?  

A.  Genistein
B.  Morphine
C.  Quinine
D.  Taxol
E.  Cyanogenic glycosides

Clarify Question
· What is the key concept addressed by the question?
· What type of thinking is required?
· What key words does the question contain and what do they mean?

Gather Content
· What do you already know about a secondary plant metabolite that can be used as a pain reliever? How does it relate to the question?

Consider Possibilities
· What other information is related to the question? Which information is most useful?

Choose Answer
· Given what you now know, what information and/or problem solving approach is most likely to produce the correct answer?

Reflect on Process
· Did your problem-solving process lead you to the correct answer? If not, where did the process break down or lead you astray? How can you revise your approach to produce a more desirable result?


B.  Morphine

Clarify Question
· What is the key concept addressed by the question?
        o This question is asking about the secondary plant metabolite that can be used as a pain reliever.
· What type of thinking is required?
        o You are being asked to take what you already know and apply it to the use of secondary plant metabolites for human pain relief.
· What key words does the question contain and what do they mean?
        o Analgesic, which is a substance that relieves pain.
        o Secondary plant metabolite, which is a substance that is made by a plant, but is not necessary for the survival of the plant.

Gather Content
· What do you already know about a secondary plant metabolite that can be used as a pain reliever? How does it relate to the question?
        o Morphine is a secondary plant metabolite.
        o Morphine has pain-relieving properties.

Consider Possibilities
· What other information is related to the question? Which information is most useful?
        o Cyanogenic glycosides give rise to cyanide.
        o Taxol has anticancer properties.
        o Quinine is an anti-malarial agent.
        o Genistein is an estrogen mimic.

Choose Answer
· Given what you now know, what information and/or problem solving approach is most likely to produce the correct answer?
        o Morphine is the only choice that has pain-relieving properties.

Reflect on Process
· Did your problem-solving process lead you to the correct answer? If not, where did the process break down or lead you astray? How can you revise your approach to produce a more desirable result?
· Apply level:
        o This question asked you to assess which secondary plant metabolite can relieve pain. Answering this question correctly depended on your ability to use the characteristic of plant secondary metabolites in a new situation. If you got the correct answer, great job! If you got an incorrect answer, where did the process break down? Did you remember that morphine relieves pain, or that morphine is a secondary plant metabolite? Did you have trouble extending the properties of secondary plant metabolites to determine the correct answer?

Biology & Microbiology

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