Which of the following is most likely to occur when a tumor-suppressor gene is mutated?
A. The resulting tumor-suppressor protein would further suppress cell proliferation.
B. The tumor-suppressor gene and resulting protein may lose its function and ability to suppress cell proliferation.
C. The tumor-suppressor gene may be overactive.
D. The resulting tumor-suppressor protein would activate an oncogene.
E. None of the choices are possible.
Answer: B
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