What might be indicated by failure of the patient's temperature to normalize 4 or 5 days after the start of antibiotic therapy? 1. A closed-space infection 2. Drug fever 3. A missed pathogen
a. 1 and 2 only
b. 2 and 3 only
c. 1 only
d. 1, 2, and 3
ANS: D
Failure of the patient's temperature to normalize within 4 or 5 days suggests the following possi-bilities: a missed pathogen, a metastatic or closed-space infection (e.g., empyema), drug fever, or the presence of an obstructing endobronchial lesion.
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