A nurse is trying to evaluate understanding of dopamine agonists in a nursing student caring for a patient with Parkinson's disease
Which statement made by the student best demonstrates an understanding of the use of dopamine agonists in Parkinson's disease?
a. Dopamine agonists are more effective than levodopa (Dopar).
b. Dopamine agonists compete with dietary proteins in the intestines.
c. Dopamine agonists are more likely to cause permanent and disabling dyskinesias.
d. Non-ergot derivatives cause fewer side effects than ergot derivatives such as bromocriptine (Parlodel).
ANS: D
The non-ergot derivatives cause fewer side effects than the ergot derivatives, because the non-ergot drugs are selective for dopamine receptors. Ergot derivatives interact with alpha-adrenergic and serotonergic receptors in addition to dopamine receptors.
Dopamine agonists are not more effective than levodopa.
Dopamine agonists do not compete with dietary proteins in the intestines.
Dopamine agonists are not more likely to cause permanent and disabling dyskinesias.
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