Which of the following is an inherited disorder with pancytopenia, malformed kidneys, and mental deficiency?
a. Myelodysplasia
b. Fanconi anemia
c. Diamond-Blackfan anemia
d. Secondary aplastic anemia
ANS: B
Fanconi anemia is an autosomal recessive disorder, which means that the gene must be inherited from both parents to express the phenotype. Myelodysplasia and secondary aplastic anemia are both acquired. Diamond-Blackfan anemia is an inherited form of pure red cell aplasia (PRCA). Neutrophil and platelet precursors are normal.
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