Congenital non-spherocytic haemolyic anaemia (CNSHA) is caused by a mutation of one or more of the enzymes of the glycolytic pathway. The most common is a mutation in the gene for pyruvate kinase resulting in a non-functional enzyme. Patients with CNSHA often show marked ATP deficiencies. Given what you know about this enzyme’s action, why would this be expected?
a. Pyruvate kinase produces ATP when it phosphorylates glucose to glucose-6-phosphate.
b. Pyruvate kinase uses excess ATP when it phosphorylates fructose-6-phosphate.
c. Pyruvate kinase produces ATP when it generates pyruvate from phosphophoenolpyruvate (PEP).
d. Pyruvate kinase uses excess ATP when it catalyzes the dehydration of 2-phosphoglycerate.
c. Pyruvate kinase produces ATP when it generates pyruvate from phosphophoenolpyruvate (PEP).
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A. 0 and 10% B. 0 and 25% C. 0 and 50% D. 0 and 75% E. 0 and 100%
Which of the following statements best compares the ovary, ovule, and egg?
A. The three terms are synonymous. B. The ovary is the lower part of the pistil that houses the ovules (also called eggs). C. An ovule is the lower part of the pistil that houses the ovary that in turn contains the eggs. D. Ovules are small ovaries and either can produce eggs. E. The ovary is the lower part of the pistil that houses the ovules that in turn contain the eggs.
Adult cells cannot be used as the source of nuclei for cloning animals. Indicate whether the statement is true or false
Why do your parents or grandparents most likely need glasses to read?
A) The photoreceptors of the eye are no longer as responsive. B) The lens of the eye stiffens with age, making it difficult to focus on nearby objects. C) They have spent more time reading books at close range than have younger people. D) The optic nerve sends signals more slowly as people age. E) The lens of the eye becomes rounder with age.