A pregnant client's quadruple screen shows a risk for the fetus to have Down syndrome. Which test results within the screen were used to make this determination? Select all that apply
1. Inhibin-A
2. Alpha-fetoprotein (AFP)
3. Unconjugated estriol (UE)
4. Hemoglobin electrophoresis
5. Human chorionic gonadotropin (hCG)
1, 2, 3, 5
Explanation:
1. Higher than normal levels of inhibin-A may indicate that a woman is at increased risk of having a baby with Down syndrome.
2. Lower than normal AFP could indicate that the woman's child is at risk for Down syndrome or trisomy 18.
3. Lower than normal UE may indicate that a woman is at increased risk of having a baby with Down syndrome.
4. Hemoglobin electrophoresis is not a test within the quadruple screen.
5. Higher than normal levels of hCG may indicate that a woman is at increased risk of having a baby with Down syndrome.
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