The client takes diphenhydramine (Benadryl), but forgets to tell the physician about this drug when a monoamine oxidase inhibitor (MAOI) drug is prescribed for depression. What will the best assessment by the nurse reveal?
1. The depression will not subside.
2. The client may develop seizures.
3. The diphenhydramine (Benadryl) will not control allergies.
4. The client may develop a hypertensive crisis.
Correct Answer: 4
Rationale 1: Depression is not the concern with this combination.
Rationale 2: Seizures are not the concern with this combination.
Rationale 3: Control of allergies is not the concern with this combination.
Rationale 4: The combination of diphenhydramine (Benadryl) and a monoamine oxidase inhibitor (MAOI) drug can result in a hypertensive crisis.
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