Parenteral administration of antipsychotic medications:
a. avoids first pass metabolism
b. demonstrates variable absorption
c. has lower brain bioavailability
d. has slower clinical effectiveness
A
Parenteral administration of antipsychotic medications avoids first pass metabolism. As a result of this, medications administered parenterally work faster and have greater clinical effect, due to higher brain bioactivity. In the case of medications not administered parenterally, many times they are rapidly metabolized by the liver before reaching the bloodstream.
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