A nurse is discussing the use of immunosuppressants for the treatment of inflammatory bowel disease (IBD) with a group of nursing students. Which statement by a student indicates understanding of the teaching?
a. "Azathioprine (Imuran) helps induce rapid remission of IBD."
b. "Cyclosporine (Sandimmune) can be used to induce remission of IBD."
c. "Cyclosporine (Sandimmune) does not have serious adverse effects."
d. "Methotrexate is used long term to maintain remission of IBD."
ANS: B
Cyclosporine can be given intravenously to induce rapid remission of IBD. Azathioprine has delayed onset of effects up to 6 months and is not used to induce rapid remission. Cyclosporine is a toxic compound that can cause renal impairment, neurotoxicity, and immune suppression. Methotrexate is used to promote short-term remission.
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