Explain how the SRY gene induces the development of testes and the male reproductive tract

What will be an ideal response?


ANSWER: The SRY gene becomes active in the seventh week of embryonic development. The protein
encoded by the gene sets a molecular switch that causes the primitive gonads to develop
into testes. The fetal testes then secrete two hormones, testosterone and the anti-Müllerian
hormone (AMH). The testosterone stimulates development of the Wolffian ducts into the
male reproductive tract, including the epididymis, vas deferens, and seminal vesicles.
Testosterone additionally stimulates the development of the male genitalia. AMH
stimulates Müllerian duct regression.

Biology & Microbiology

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