How could overlapping genes in a positive ssDNA virus genome be predicted?

A) Convert the positive ssDNA into its complementary ssDNA and search for genes in the negative ssDNA strand for sequences used in more than one predicted gene.
B) Directly search the three frames of the positive ssDNA for genes that have sequences where more than one gene is predicted.
C) Convert the positive ssDNA into negative ssDNA and search all six possible frames for genes that use part of the same sequence.
D) Convert the positive ssDNA into its complementary ssDNA and search for genes in the negative ssDNA strand that also share a complementary gene in the positive strand.


Answer: B

Biology & Microbiology

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