Thirty minutes after Mary has completed a 25-km race, she begins to notice severe muscle soreness and stiffness in her legs. Her urine is dark colored. She wonders whether she may have damaged her muscles during the race. She visits the ER, and the doctor orders several blood tests. What kind of blood tests can help determine whether muscle damage has occurred?


If muscle damage occurred, the doctor would find enzymes such as creatine kinase and proteins such as myoglobin or troponin in the bloodstream released by injured skeletal muscle cells. The level of these substances correlates with the severity of the injury.

Anatomy & Physiology

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