A client is receiving donepezil. When reviewing the client's medication history, the nurse determines that the client is at increased risk for GI bleeding if the client is also taking which drug? Select all that apply
A) Naproxen (Naprosyn)
B) Oxycodone (OxyContin)
C) Acetaminophen (Tylenol)
D) Ibuprofen (Motrin)
E) Meperidine (Demerol)
Ans: A, D
Feedback:
Use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as naproxen or ibuprofen, in combination with donepezil place the client at an increased risk for GI bleeding. Oxycodone, acetaminophen, and meperidine do not increase the client's risk.
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