A client is experiencing muscle atrophy following 2 weeks in traction after a motor vehicle accident. Which of the following factors has most likely contributed to the atrophy of the client's muscle cells?
A)
High levels of insulin and IGF-1 in the client's blood during immobilization
B)
Denervation of the affected muscles during the time of traction
C)
A reduction of skeletal muscle use secondary to the traction treatment
D)
Reduced oxygen consumption and cellular function that ensures muscle cell survival
Ans:
C
Feedback:
Disuse atrophy results from the reduction in skeletal muscle use such as that following encasement in plaster casts or traction. Low levels of insulin and IGF-1 contribute to atrophy, and denervation only occurs in paralyzed limbs. Reduced oxygen consumption and cellular function are the mechanisms of cell atrophy but not the causes of the process.
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